Prostate Cancer Information
UPOINT System for the Clinical Phenotyping of Chronic Pelvic Pain (Chronic Prostatitis/Chronic Pelvic Pain Syndrome, Interstitial Cystitis, Painful Bladder Syndrome)
Patients with the urologic pelvic pain syndromes have diverse and often multiple etiologies. The best treatment outcomes are achieved with multimodal therapy. The UPOINT system is designed to classify patients with an established diagnosis of CP/CPPS and IC into a clinically relevant phenotype that can rationally guide therapy. Using this website, physicians can classify their patients into the six domains of the UPOINT system (Urinary, Psychosocial, Organ Specific, Infection, Neurologic/Systemic, Tenderness of Skeletal Muscles) and review treatment choices based upon that phenotype. For more information about the UPOINT system and chronic pelvic pain syndromes, please see the FAQ page
This web tool is meant to classify patients who have an established diagnosis of CP/CPPS or IC. It is NOT designed to diagnose these conditions. The symptoms of these conditions overlap with many other Urologic and Non-Urologic diseases including cancer, stones, infections and other potentially life threatening conditions. The menu of domain specific therapies is for general guidance only and obviously does not take into account the patient's past therapies, allergies, and interactions with current medications. By using this website, the user acknowledges that the diagnosis of CP/CPPS or IC must first be made by a licensed physician with expertise in this field and that the list of possible therapies is for guidance only and does NOT represent medical advice. This website is designed for use by physicians. Any patient who uses this site understands that only a physician can diagnose these conditions and agrees that use of the site IN NO WAY creates a therapeutic relationship.
In order to use this site, you will be asked for results of the NIH-CPSI score in men and the UPP Index score in women. If you need copies of these scores, you may download them below. Not every test listed is required to phenotype the patient (eg. cystoscopy with hydrodistension, TRUS in a male) but as a minimum we suggest the following:

Urinary: A post void residual measured by ultrasound

Psychosocial: Ask about clinical depression and catastrophizing (helplessness and hopelessness about the condition)

Organ specific: Pain improvement with bladder emptying, tenderness of the prostate

Infection: Culture for mycoplasma and ureasplasma, culture of urine and (in men) expressed prostatic secretions or a post-prostate massage urine

Neurologic/Systemic: Ask about pain outside the pelvis and a diagnosis of other pain syndromes

Tenderness: Palpate the abdominal and pelvic skeletal muscles (via rectum or vagina) and check for spasm and trigger points

If you need the male or female symptom scores, you can download them here


Female Urologic Pelvic Pain Index

   I agree with Terms & Conditions